Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MDH1 | P40925 | 1/20 | 0.34 |
| ▸ | MDH2 | P40926 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430678 | 0.86 | ELANE (0.43) | KMT2AMEN1FAAHCNR2ELANE | |
| SCHEMBL7601488 | 0.86 | ELANE (0.37) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL30518984 | 0.82 | KMT2A (0.36) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL26304702 | 0.82 | KMT2A (0.36) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL8730904 | 0.81 | KMT2A (0.42) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL8733834 | 0.80 | KMT2A (0.42) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL2626945 | 0.79 | FAAH (0.43) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL30518974 | 0.79 | FAAH (0.43) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL26304032 | 0.79 | SMN1; SMN2 (0.40) | KMT2AMEN1FAAHCNR2ALDH1A1 | |
| SCHEMBL5165364 | 0.74 | CNR2 (0.34) | KMT2AMEN1FAAHCNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497972-B1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX INC (US) | 1998-12-23 | — | — | EP | disclosed |