Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734798 | 0.86 | SLC18A3 (0.66) | SLC18A3GRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL8736183 | 0.86 | SLC18A3 (1.00) | SLC18A3SIGMAR1GRIN2DGRIN3BADRA1D | |
| SCHEMBL9341163 | 0.85 | SLC18A3 (0.65) | SLC18A3SIGMAR1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8733371 | 0.82 | SLC18A3 (0.61) | SLC18A3GRIN2BDRD2 | |
| SCHEMBL8734718 | 0.81 | SLC18A3 (0.70) | SLC18A3GRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL8736198 | 0.80 | ADRA2A (0.58) | SLC18A3 | |
| SCHEMBL8937206 | 0.80 | SLC18A3 (0.79) | SLC18A3SIGMAR1GRIN2DGRIN3BADRA1D | |
| SCHEMBL7544920 | 0.79 | SLC18A3 (0.77) | SLC18A3SIGMAR1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8736265 | 0.77 | SLC18A3 (0.55) | SLC18A3SIGMAR1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8734239 | 0.76 | SLC18A3 (0.72) | SLC18A3GRIN2DGRIN3BADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721243-A | ANTICHOLINERGIC AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0576611-A4 | RADIOPHARMACEUTICAL AGENTS FOR THE DETECTION OF ALZHEIMER'S DISEASE | UNIV MINNESOTA (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5358712-A | For binding to receptors when monitoring for cholinergic innervation in living brains, detection of Alzheimer*s disease | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0576611-A1 | RADIOPHARMACEUTICAL AGENTS FOR THE DETECTION OF ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016239-A1 | RADIOPHARMACEUTICAL AGENTS FOR THE DETECTION OF ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-10-01 | — | — | WO | disclosed |