Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543588 | 0.86 | PARP10 (0.40) | PARP10APPPRSS1PRSS2PRSS3 | |
| SCHEMBL5540184 | 0.84 | APP (0.41) | APPNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL6741410 | 0.83 | PARP10 (0.54) | PARP10PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL7253353 | 0.80 | MEN1 (0.39) | PARP10PRSS1PRSS2PRSS3RAB9A | |
| SCHEMBL542723 | 0.78 | MAOB (0.47) | APPMAOB | |
| SCHEMBL543113 | 0.77 | MAOB (0.54) | PARP10APPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7249694 | 0.76 | PARP10 (0.51) | PARP10APPPRSS1PRSS2PRSS3 | |
| SCHEMBL7253638 | 0.76 | IDO1 (0.45) | APPMAOB | |
| SCHEMBL863820 | 0.76 | GSK3B (0.49) | APPMAOB | |
| SCHEMBL7246097 | 0.76 | MAOB (0.46) | PARP10APPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |