SCHEMBL8734332

SCHEMBL8734332

C=CCc1cc(O)ccc1OP(=O)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.39
PTGDR Q13258 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
CAMK2A Q9UQM7 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SRC P12931 1/20 0.36
MAPT P10636 2/20 0.34
THRB P10828 1/20 0.34
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALOX5 P09917 1/20 0.33
GABRA1 P14867 1/20 0.33
CNR2 P34972 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7656121 1.00 ELANE (0.39) ELANEPTGDRPTGDR2CAMK2AMEN1
SCHEMBL13002803 0.84 ELANE (0.36) ELANEPTGDRPTGDR2MEN1KMT2A
SCHEMBL3801608 0.83 KDM4E (0.42) SRC
SCHEMBL2142447 0.83 KDM4E (0.42) SRC
SCHEMBL21883503 0.81 ELANE (0.41) ELANEPTGDRPTGDR2MEN1KMT2A
SCHEMBL13337570 0.79 MEN1 (0.37) ELANEPTGDRPTGDR2MEN1KMT2A
SCHEMBL13789695 0.78 TDP1 (0.46) ELANEPTGDRPTGDR2MEN1KMT2A
SCHEMBL541751 0.75 KDM4E (0.44) TDP1
SCHEMBL31127744 0.75 KDM4E (0.44) TDP1
SCHEMBL7656115 0.75 GABRA1 (0.40) MEN1KMT2ASRCMAPTGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5817857-A (4-Hydroxy-alkylphenyl diphenyl phosphate flame rerardants AKZO NOBEL NV (NL) 1998-10-06 US disclosed