Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL8730890 | 0.92 | TDP1 (0.59) | TDP1LMNAALDH1A1THRBTSHR | |
| Glycerin SCHEMBL9064954 | 0.89 | LMNA (0.56) | TDP1LMNAALDH1A1THRBTSHR | |
| Glycerin SCHEMBL11848316 | 0.88 | TDP1 (0.48) | TDP1LMNAALDH1A1THRBTSHR | |
| Glycerin SCHEMBL8462303 | 0.87 | TDP1 (0.67) | TDP1LMNAALDH1A1THRBTSHR | |
| Propylene Glycol SCHEMBL8832136 | 0.87 | — | — | |
| Glycerin SCHEMBL8328163 | 0.84 | LMNA (0.64) | TDP1LMNAALDH1A1THRBOR51E2 | |
| Glycerin SCHEMBL4538901 | 0.84 | LMNA (0.64) | TDP1LMNAALDH1A1THRBOR51E2 | |
| Glycerin SCHEMBL8537586 | 0.81 | LMNA (0.53) | TDP1LMNAALDH1A1THRBTSHR | |
| Glycerin SCHEMBL27534587 | 0.81 | LMNA (0.60) | TDP1LMNAALDH1A1THRBOR51E2 | |
| Glycerin SCHEMBL11032789 | 0.81 | LMNA (0.60) | TDP1LMNAALDH1A1THRBOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998019545-A1 | COMPOSITION AND METHOD FOR THE TREATMENT OF VAGINAL YEAST INFECTIONS | REINHARD MARK S (US) | 1998-05-14 | — | — | WO | disclosed |