Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734379 | 1.00 | RARB (0.45) | RARBRARAPTPN11RARGPTPN1 | |
| SCHEMBL8734381 | 1.00 | RARB (0.45) | RARBRARAPTPN11RARGPTPN1 | |
| SCHEMBL8729757 | 0.89 | PTPN11 (0.41) | RARBRARAPTPN11THRBPPARG | |
| SCHEMBL8729762 | 0.89 | PTPN11 (0.41) | RARBRARAPTPN11THRBPPARG | |
| SCHEMBL8729765 | 0.89 | PTPN11 (0.41) | RARBRARAPTPN11THRBPPARG | |
| SCHEMBL8733509 | 0.89 | NPC1 (0.47) | RARBRARAPTPN11THRBTHRA | |
| SCHEMBL8733514 | 0.89 | NPC1 (0.47) | RARBRARAPTPN11THRBTHRA | |
| SCHEMBL8733511 | 0.89 | NPC1 (0.47) | RARBRARAPTPN11THRBTHRA | |
| SCHEMBL8733460 | 0.87 | RARB (0.45) | RARBRARAPTPN11RARGPTPN1 | |
| SCHEMBL8733462 | 0.87 | RARB (0.45) | RARBRARAPTPN11RARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703955-B1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECR DEFENCE BRIT (GB) | 1998-11-11 | — | — | EP | disclosed |
| EP-0703955-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029405-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1994-12-22 | — | — | WO | disclosed |