Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729757 | 1.00 | PTPN11 (0.41) | PTPN11RARARARBMCL1PPARD | |
| SCHEMBL8729765 | 1.00 | PTPN11 (0.41) | PTPN11RARARARBMCL1PPARD | |
| SCHEMBL8734379 | 0.89 | RARB (0.45) | PTPN11RARARARBPPARDTHRB | |
| SCHEMBL8734384 | 0.89 | RARB (0.45) | PTPN11RARARARBPPARDTHRB | |
| SCHEMBL8734381 | 0.89 | RARB (0.45) | PTPN11RARARARBPPARDTHRB | |
| SCHEMBL8733455 | 0.89 | PTPN11 (0.39) | PTPN11RARARARBPPARDTHRB | |
| SCHEMBL8733452 | 0.89 | PTPN11 (0.39) | PTPN11RARARARBPPARDTHRB | |
| SCHEMBL8733500 | 0.87 | NPC1 (0.47) | PTPN11RARBTHRBNFKB1NFKB2 | |
| SCHEMBL8731362 | 0.87 | THRA (0.43) | PTPN11RARBPPARDTHRBNFKB1 | |
| SCHEMBL8731273 | 0.86 | PTPN11 (0.41) | PTPN11RARARARBPPARDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703955-B1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECR DEFENCE BRIT (GB) | 1998-11-11 | — | — | EP | disclosed |