Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734074 | 0.79 | TDP1 (0.36) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| SCHEMBL1262441 | 0.72 | CYP3A4 (0.41) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| SCHEMBL7056051 | 0.70 | CA1 (0.41) | — | |
| SCHEMBL28923865 | 0.69 | CYP3A4 (0.36) | CYP3A4TDP1TSHRMAPTCACNA1B | |
| SCHEMBL9237824 | 0.66 | CYP3A4 (0.39) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| SCHEMBL170054 | 0.66 | CYP3A4 (0.39) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| SCHEMBL18177929 | 0.66 | TSHR (0.41) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| SCHEMBL9579854 | 0.66 | CYP3A4 (0.36) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| Phosphoric Acid SCHEMBL27960576 | 0.65 | CYP3A4 (0.42) | CYP3A4PKMSMN1; SMN2TDP1TSHR | |
| SCHEMBL18177935 | 0.65 | CYP3A4 (0.38) | CYP3A4PKMSMN1; SMN2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-A4 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 1998-02-25 | — | — | EP | claimed |
| EP-0792275-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996015132-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-23 | — | — | WO | claimed |