Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734504 | 0.79 | CYP3A4 (0.32) | TDP1PKMSMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL9579858 | 0.76 | TSHR (0.40) | TDP1PKMSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL11498319 | 0.76 | TSHR (0.43) | TDP1PKMSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL5823328 | 0.75 | TSHR (0.44) | TDP1PKMSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL7052022 | 0.70 | CA1 (0.39) | TDP1PKMSMN1; SMN2TSHR | |
| SCHEMBL14681170 | 0.70 | TSHR (0.47) | TDP1PKMSMN1; SMN2TSHRNPSR1 | |
| Butane SCHEMBL2392562 | 0.69 | TSHR (0.51) | TDP1PKMSMN1; SMN2TSHRNPSR1 | |
| Phosphoric Acid SCHEMBL27674703 | 0.69 | TSHR (0.55) | TDP1PKMSMN1; SMN2TSHRNPSR1 | |
| SCHEMBL28923865 | 0.68 | CYP3A4 (0.36) | TDP1TSHRCYP3A4 | |
| SCHEMBL1907257 | 0.68 | TDP1 (0.42) | TDP1PKMSMN1; SMN2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-A4 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 1998-02-25 | — | — | EP | claimed |
| EP-0792275-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996015132-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-23 | — | — | WO | claimed |