SCHEMBL8734579

SCHEMBL8734579

C=CC(=O)OC(OCCC[Si](OC)(OC)OC)C(C)O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HPGD P15428 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18669159 0.85 TSHR (0.42) TSHRHPGDALDH1A1CYP3A4
SCHEMBL2805758 0.84 TSHR (0.35) TSHRHPGDALDH1A1CYP3A4
SCHEMBL14764358 0.84 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4
SCHEMBL10949665 0.81 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4
SCHEMBL27783779 0.78 TSHR (0.45) TSHRHPGDALDH1A1CYP3A4
SCHEMBL2462828 0.77 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4
SCHEMBL8863720 0.75 TSHR (0.34) TSHRHPGDALDH1A1CYP3A4
SCHEMBL21359749 0.75 TSHR (0.37) TSHRHPGDALDH1A1CYP3A4
SCHEMBL71730 0.74 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4
SCHEMBL21357993 0.74 TSHR (0.36) TSHRHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9399335-B2 Adhesive for producing composite bodies, a plastic glass composite or composite glass for architecture and construction EVONIK RÖHM GMBH (DE) 2016-07-26 US disclosed
EP-2817379-B1 ADHESIVE FOR PRODUCING COMPOUND BODIES, PRIMARILY A PLASTIC-GLASS COMPOUND OR COMPOUND GLASS, FOR ARCHITECTURE AND CONSTRUCTION EVONIK ROEHM GMBH (DE) 2016-04-13 EP disclosed
EP-2817379-A1 ADHESIVE FOR PRODUCING COMPOSITE BODIES, PREFERABLY OF A PLASTIC-GLASS COMPOSITE OR COMPOSITE GLASS, FOR ARCHITECTURE AND CONSTRUCTION Evonik Industries AG (DE) 2014-12-31 EP disclosed
US-20140349093-A1 ADHESIVE FOR PRODUCING COMPOSITE BODIES, PREFERABLY OF A PLASTIC-GLASS COMPOSITE OR COMPOSITE GLASS, FOR ARCHITECTURE AND CONSTRUCTION EVONIK INDUSTRIES AG (DE) 2014-11-27 US disclosed
WO-2013124210-A1 ADHESIVE FOR PRODUCING COMPOSITE BODIES, PREFERABLY OF A PLASTIC-GLASS COMPOSITE OR COMPOSITE GLASS, FOR ARCHITECTURE AND CONSTRUCTION EVONIK INDUSTRIES AG (DE) 2013-08-29 WO disclosed
EP-0659786-B1 Plastic sanitary objects with better properties ROEHM GMBH (DE) 1998-03-18 EP disclosed
EP-0659786-A1 Plastic sanitary objects with better properties Röhm GmbH (DE) 1995-06-28 EP disclosed