SCHEMBL2462828

SCHEMBL2462828

C=CC(=O)OC(OCCOCCOC(OC(=O)C=C)C(C)O)C(C)O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
ALDH1A1 P00352 3/20 0.46
TP53 P04637 2/20 0.46
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.34
CYP3A4 P08684 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18669159 0.88 TSHR (0.42) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL14764358 0.86 TSHR (0.46) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10949665 0.83 TSHR (0.51) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL2853889 0.81 TSHR (0.45) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL27783779 0.81 TSHR (0.45) TSHRALDH1A1THRBHPGDCYP3A4
SCHEMBL1637419 0.77 TSHR (0.42) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8734579 0.77 TSHR (0.33) TSHRALDH1A1HPGDCYP3A4
SCHEMBL2465350 0.76 THRB (0.41) TSHRALDH1A1THRBMEN1KMT2A
SCHEMBL9862506 0.76 TSHR (0.41) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL27541066 0.76 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632281-B1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM & HAAS (US) 2011-09-14 EP disclosed
EP-1510318-B1 Process for manufacturing polymers ROHM & HAAS (US) 2009-07-01 EP disclosed
US-7312259-B2 combining polymers with surfactants having hydrophilic-lipophilic balance values between 10 and 25 via spray drying, to lower or reduce the dusting levels, raise the minimum ignition energy and lower explosion strength during handling, conveying and storage ROHM AND HAAS COMPANY (US) 2007-12-25 US disclosed
EP-1092421-B1 Method for preparing ultraviolet radiation absorbing compositions ROHM & HAAS (US) 2007-03-21 EP disclosed
US-7192542-B2 Oil absorbing composition and process ROHM AND HAAS COMPANY (US) 2007-03-20 US disclosed
EP-1632281-A1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM AND HAAS COMPANY (US) 2006-03-08 EP disclosed
US-20050203215-A1 Polymer carriers and process UGAZIO STEPHEN P J (FR) 2005-09-15 US disclosed
EP-1574534-A1 Polymer carriers and process ROHM AND HAAS COMPANY (US) 2005-09-14 EP disclosed
US-20050131143-A1 Oil absorbing composition and process ROHM AND HAAS FRANCE, S.A.S. (FR) 2005-06-16 US disclosed
EP-1514658-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-16 EP disclosed
EP-1510318-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-02 EP disclosed
US-20050043458-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY 2005-02-24 US disclosed
US-20050043453-A1 Process for manufacturing polymers CHANG CHING-JEN (US) 2005-02-24 US disclosed
US-6384104-B1 PROVIDING STORAGE STABILITY TO ULTRAVIOLET RADIATION ABSORPTION COMPOSITIONS BY ADDING LATEX POLYMER PARTICLES TO INCREASE ABSORPTION, WHEREIN PARTICLES CONTAIN VOID, HAVE SPECIFIED PARTICLE SIZE AND COMPRISE CROSSLINKED SHELL PORTION ROHM AND HAAS COMPANY 2002-05-07 US disclosed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP disclosed