Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358348 | 1.00 | TSHR (0.41) | TSHRPPARDMAPTMAPK1TP53 | |
| SCHEMBL9653714 | 0.81 | GLO1 (0.40) | TSHRPPARDMAPTMAPK1 | |
| SCHEMBL5873561 | 0.81 | GLO1 (0.40) | TSHRPPARDMAPTMAPK1 | |
| SCHEMBL28361944 | 0.81 | TSHR (0.39) | TSHRPPARDMAPTMAPK1TP53 | |
| SCHEMBL8576108 | 0.81 | GLO1 (0.40) | TSHRPPARDMAPTMAPK1 | |
| SCHEMBL8165454 | 0.80 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL9491442 | 0.80 | FNTA (0.32) | FNTAFNTB | |
| SCHEMBL2458072 | 0.79 | TSHR (0.48) | TSHRPPARDMAPTTP53TDP1 | |
| SCHEMBL9617956 | 0.79 | GABRR1 (0.41) | TSHRPPARDMAPTMAPK1TP53 | |
| SCHEMBL10333808 | 0.79 | GABRR1 (0.41) | TSHRPPARDMAPTMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717128-A | HEATING AN ESTER OF 2-HYDROXY-2-METHYL-3-BUTENOIC ACID WITH PHOSPHOROUS BROMIDE OR CHLORIDE; THEN WITH TRIALKYL ESTER OF PHOSPHOROUS ACID | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| US-4937308-A | Preparation of alkyl O,O-dialkyl-γ-phosphonotiglates | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-26 | — | — | US | disclosed |