SCHEMBL8734759

SCHEMBL8734759

CCCCCC/C=C/C=C/[SiH2][O]

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.55
FASN P49327 1/20 0.53
FAAH O00519 6/20 0.49
TRPV1 Q8NER1 1/20 0.48
KDM4E B2RXH2 1/20 0.45
CNR1 P21554 3/20 0.42
CNR2 P34972 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734762 1.00 TSHR (0.55) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL8731704 0.85 FAAH (0.54) TSHRFAAHTRPV1
SCHEMBL8731706 0.85 FAAH (0.54) TSHRFAAHTRPV1
SCHEMBL1983164 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL23040320 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL23040318 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL23040319 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL8777247 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3678163 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1
SCHEMBL3685051 0.82 TSHR (0.68) TSHRALDH1A1FASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5795947-A RELEASE PAPER COATINGS RHONE-POULENC CHIMIE (FR) 1998-08-18 US disclosed
EP-0632085-A1 Silicone polymers having olefinic functional groups, process for their preparation, and curable compositions comprising them RHONE-POULENC CHIMIE (FR) 1995-01-04 EP disclosed