Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17355359 | 0.79 | LMNA (0.55) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL13721282 | 0.78 | LMNA (0.61) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL2222746 | 0.78 | LMNA (0.61) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL11804343 | 0.78 | LMNA (0.54) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL15633275 | 0.78 | LMNA (0.54) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL32687952 | 0.78 | LMNA (0.65) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL17355364 | 0.78 | LMNA (0.65) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL11146534 | 0.76 | LMNA (0.63) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL11146531 | 0.76 | LMNA (0.63) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| Ethyl Cinnamate SCHEMBL112446 | 0.76 | CA12 (0.72) | LMNAAKR1B10AKR1B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998040078-A1 | THERAPEUTIC AUGMENTATION OF OXYALKYLENE DIESTERS AND BUTYRIC ACID DERIVATIVES | BEACON LABORATORIES, INC. (US) | 1998-09-17 | — | — | WO | claimed |