SCHEMBL8734930

SCHEMBL8734930

CCC1(Cl)C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
PKM P14618 1/20 0.34
OXTR P30559 1/20 0.31
CACNB4 O00305 1/20 0.31
CACNA1A O00555 1/20 0.31
CACNA1G O43497 1/20 0.31
CACNG3 O60359 1/20 0.31
CACNA1F O60840 1/20 0.31
CACNA1H O95180 1/20 0.31
CACNB3 P54284 1/20 0.31
CACNA2D1 P54289 1/20 0.31
CACNG7 P62955 1/20 0.31
CACNA1B Q00975 1/20 0.31
CACNA1D Q01668 1/20 0.31
CACNB1 Q02641 1/20 0.31
CACNG1 Q06432 1/20 0.31
CACNB2 Q08289 1/20 0.31
CACNA1S Q13698 1/20 0.31
CACNA1C Q13936 1/20 0.31
CACNA1E Q15878 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4660513 0.77 KDM4E (0.37) KDM4EPKMOXTRMCHR2MCHR1
SCHEMBL11503389 0.73 KDM4E (0.35) KDM4EPKMOXTRMCHR2MCHR1
SCHEMBL27688571 0.73 KDM4E (0.35) KDM4EPKMOXTRMCHR2MCHR1
SCHEMBL8737325 0.72 OXTR (0.33) KDM4EPKMOXTRCACNB4CACNA1A
SCHEMBL27707605 0.72 KDM4E (0.34) KDM4EPKMOXTRMCHR2MCHR1
Iodide SCHEMBL27932889 0.72 KDM4E (0.34) KDM4EPKMOXTRMCHR2MCHR1
SCHEMBL17008829 0.72 KDM4E (0.34) KDM4EPKMOXTRMCHR2MCHR1
SCHEMBL28073498 0.72 KDM4E (0.34) KDM4EPKMOXTRMCHR2MCHR1
SCHEMBL18242424 0.72 KDM4E (0.34) KDM4EPKMOXTRMCHR2MCHR1
Hydrochloric Acid SCHEMBL27932978 0.72 KDM4E (0.34) KDM4EPKMOXTRMCHR2MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0642483-B1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF DOW CHEMICAL CO (US) 1998-02-18 EP disclosed
EP-0642483-A4 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF. 1995-04-19 EP disclosed
EP-0642483-A1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1995-03-15 EP disclosed
US-5227560-A Vinylene or exomethylene groups from active methine compounds THE DOW CHEMICAL COMPANY (US) 1993-07-13 US disclosed
WO-1993009078-A1 CHLORINATION AND ELIMINATION PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO disclosed