SCHEMBL8734955

SCHEMBL8734955

CC=CC(=O)OCC(O)COCCC[Si](OC)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331749 0.87 ATM (0.31) LPAR5
SCHEMBL996290 0.85 LPAR5 (0.37) LPAR5KDM4ECYP1A2SMN1; SMN2
SCHEMBL1046295 0.85 LPAR5 (0.41) LPAR5KDM4ECYP1A2SMN1; SMN2
SCHEMBL15210394 0.85 TSHR (0.42) LPAR5KDM4ELMNACYP1A2SMN1; SMN2
SCHEMBL4255755 0.84 LPAR5 (0.43) LPAR5KDM4ELMNACYP1A2SMN1; SMN2
SCHEMBL21081953 0.84 LPAR5 (0.43) LPAR5KDM4ELMNACYP1A2SMN1; SMN2
SCHEMBL21081952 0.84 LPAR5 (0.43) LPAR5KDM4ELMNACYP1A2SMN1; SMN2
SCHEMBL21081955 0.84 LPAR5 (0.43) LPAR5KDM4ELMNACYP1A2SMN1; SMN2
SCHEMBL12094888 0.84 LPAR5 (0.31) LPAR5
SCHEMBL28344750 0.84 TSHR (0.41) LPAR5KDM4ELMNACYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659786-B1 Plastic sanitary objects with better properties ROEHM GMBH (DE) 1998-03-18 EP disclosed
EP-0659786-A1 Plastic sanitary objects with better properties Röhm GmbH (DE) 1995-06-28 EP disclosed