SCHEMBL331749

SCHEMBL331749

CC=CC(=O)OCC(O)COCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.31
LPAR5 Q9H1C0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14842526 0.90 ATM (0.31) ATMLPAR5
SCHEMBL1284119 0.90 ATM (0.31) ATMLPAR5
SCHEMBL12094888 0.87 LPAR5 (0.31) LPAR5
SCHEMBL8734955 0.87 LPAR5 (0.31) LPAR5
SCHEMBL411296 0.86 TSHR (0.41) LPAR5
SCHEMBL22712844 0.85 ATM (0.37) ATMLPAR5
SCHEMBL8644260 0.83 ATM (0.44) ATM
SCHEMBL35808 0.83 ATM (0.44) ATM
SCHEMBL996290 0.83 LPAR5 (0.37) ATMLPAR5
SCHEMBL1046295 0.83 LPAR5 (0.41) ATMLPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
US-20220380509-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2022-12-01 US claimed
US-11453736-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2022-09-27 US claimed
US-11360241-B2 Biomedical devices containing internal wetting agents JOHNSON & JOHNSON VISION CARE, INC. (US) 2022-06-14 US claimed
EP-3598181-B1 VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME ALCON INC (CH) 2021-06-23 EP claimed
EP-1534759-A1 MACROMER FORMING CATALYSTS Johnson & Johnson Vision Care, Inc. (US) 2005-06-01 EP claimed
WO-2005005517-A2 SILICONE HYDROGELS HAVING CONSISTENT CONCENTRATIONS OF MULTI-FUNCTIONAL POLYSILOXANES JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-01-20 WO claimed
EP-1425052-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS Johnson & Johnson Vision Care, Inc. (US) 2004-06-09 EP claimed
EP-1425053-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS Johnson & Johnson Vision Care, Inc. (US) 2004-06-09 EP claimed
US-20040002556-A1 Macromer forming catalysts JOHNSON & JOHNSON VISION CARE, INC. 2004-01-01 US claimed
WO-2004000888-A1 MACROMER FORMING CATALYSTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-12-31 WO claimed
US-20030162862-A1 Contact lenses for extended wear (without surface treatment, coating-free), formed by reacting polyvinylpyrrolidone and (2-methacryloxy-3-hydroxypropyloxy)propylbis(trimethylsiloxy) methylsilane, then curing JOHNSON & JOHNSON VISION CARE, INC. 2003-08-28 US claimed
US-20030125498-A1 Biomedical devices containing internal wetting agents JOHNSON & JOHNSON VISION CARE, INC. 2003-07-03 US claimed
WO-2003022322-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed
WO-2003022321-A2 BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2003-03-20 WO claimed