Bromide

Bromide

SCHEMBL8735015

Br.C=C(C)C(=O)OC.CCCCP(CCCC)CCCC

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 3/20 0.47
THRB P10828 2/20 0.36
EPHX1 P07099 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ZDHHC7 Q9NXF8 1/20 0.31
CES1 P23141 1/20 0.30
THRA P10827 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8733801 0.96 ALDH1A1 (0.58) ALDH1A1TSHRTHRBEPHX1CA1
Bromide SCHEMBL8730937 0.93 ALDH1A1 (0.54) ALDH1A1TSHRTHRBEPHX1ZDHHC7
Hydrochloric Acid SCHEMBL8735034 0.89 ALDH1A1 (0.54) ALDH1A1TSHRTHRBEPHX1ZDHHC7
Hexane SCHEMBL27951935 0.86 ALDH1A1 (0.71) ALDH1A1TSHRTHRBEPHX1CA1
Heptane SCHEMBL8159285 0.84 ALDH1A1 (0.68) ALDH1A1TSHRTHRBEPHX1ZDHHC7
SCHEMBL28627394 0.81 TSHR (0.62) ALDH1A1TSHRTHRBEPHX1
Bromide SCHEMBL28739442 0.81 TSHR (0.77) ALDH1A1TSHRTHRBEPHX1
Butane SCHEMBL7941631 0.81 ALDH1A1 (0.79) ALDH1A1TSHRTHRBEPHX1
Butyl Alcohol SCHEMBL20566101 0.80 ALDH1A1 (0.62) ALDH1A1TSHRTHRBEPHX1
Methacrylic Acid SCHEMBL29175244 0.79 TSHR (0.39) ALDH1A1TSHRTHRBCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663409-B1 ANTIMICROBIAL POLYMER, CONTACT LENS, AND CONTACT LENS CARE PRODUCTS NIPPON CHEMICAL IND (JP) 1998-10-07 EP disclosed
US-5520910-A PHOSPHONIUM VINYL SALT COPOLYMERS AS BACTERICIDES NIPPON CHEMICAL INDUSTRIAL (JP) 1996-05-28 US disclosed
EP-0663409-A1 ANTIMICROBIAL POLYMER, CONTACT LENS, AND CONTACT LENS CARE PRODUCTS NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED (JP) 1995-07-19 EP disclosed