Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735116 | 1.00 | MAPT (0.39) | MAPTALDH1A1LMNACYP2C9HTR2C | |
| SCHEMBL8735112 | 1.00 | MAPT (0.39) | MAPTALDH1A1LMNACYP2C9HTR2C | |
| SCHEMBL18385887 | 0.91 | HTR2C (0.36) | MAPTALDH1A1LMNACYP2C9HTR2C | |
| SCHEMBL6457327 | 0.86 | ALDH1A1 (0.34) | MAPTALDH1A1LMNACYP2C9HTR2C | |
| SCHEMBL6457320 | 0.86 | ALDH1A1 (0.34) | MAPTALDH1A1LMNACYP2C9HTR2C | |
| SCHEMBL8048330 | 0.86 | SLC6A2 (0.38) | HTR2CIDO1DGAT1SOAT1 | |
| SCHEMBL6457872 | 0.86 | GAA (0.34) | MAPTHTR2CLSSMEN1KMT2A | |
| SCHEMBL6457875 | 0.86 | GAA (0.34) | MAPTHTR2CLSSMEN1KMT2A | |
| SCHEMBL6454054 | 0.85 | GAA (0.36) | MAPTLSSMEN1KMT2AGAA | |
| SCHEMBL6461154 | 0.85 | GAA (0.36) | MAPTLSSMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846670-A1 | CYCLOHEXANE DERIVATIVES AND LIQUID-CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1998-06-10 | — | — | EP | disclosed |