Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556584 | 1.00 | MEN1 (0.48) | MEN1KMT2AKDM1ASIGMAR1EBP | |
| SCHEMBL29556714 | 0.89 | KDM1A (0.44) | MEN1KMT2AKDM1ASIGMAR1TP53 | |
| SCHEMBL8734058 | 0.89 | KDM1A (0.44) | MEN1KMT2AKDM1ASIGMAR1TP53 | |
| SCHEMBL5138499 | 0.80 | KDM1A (0.50) | MEN1KMT2AKDM1ASIGMAR1EBP | |
| SCHEMBL8370095 | 0.78 | KDM1A (0.52) | KDM1ASIGMAR1 | |
| SCHEMBL5548497 | 0.77 | SIGMAR1 (0.49) | MEN1KMT2AKDM1ASIGMAR1EBP | |
| SCHEMBL1417844 | 0.77 | KDM1A (0.46) | MEN1KMT2AKDM1ASIGMAR1EBP | |
| SCHEMBL18428569 | 0.77 | KDM1A (0.50) | MEN1KMT2AKDM1ASIGMAR1EBP | |
| SCHEMBL29598562 | 0.77 | KDM1A (0.46) | MEN1KMT2AKDM1ASIGMAR1EBP | |
| SCHEMBL23385700 | 0.75 | KDM1A (0.49) | MEN1KMT2AKDM1ASIGMAR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546573-B1 | Process for the preparation of stabilized polyolefins and products obtained therefrom | MONTELL NORTH AMERICA INC (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0434082-B1 | Components and catalysts for the polymerization of olefins | HIMONT INC (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0362705-B1 | Catalysts for the polymerization of olefins | HIMONT INC (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5278210-A | Process for the preparation of stabilized polyolefins and products obtained therefrom | HIMONT INCORPORATED (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0546573-A1 | Process for the preparation of stabilized polyolefins and products obtained therefrom | MONTELL NORTH AMERICA INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5122492-A | Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide | HIMONT INCORPORATED (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0434082-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4978648-A | Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization | HIMONT INCORPORATED (US) | 1990-12-18 | — | — | US | disclosed |
| EP-0362705-A2 | Catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1990-04-11 | — | — | EP | disclosed |