Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885832 | 0.82 | PAM (0.50) | CYP1A2CNR2ALDH1A1HAO1PAM | |
| SCHEMBL8885838 | 0.82 | PAM (0.50) | CYP1A2CNR2ALDH1A1HAO1PAM | |
| SCHEMBL7941808 | 0.82 | CYP1A2 (0.47) | CYP1A2CNR2CYP3A4ALDH1A1HAO1 | |
| SCHEMBL1791773 | 0.81 | CYP1A2 (0.50) | CYP1A2CNR2CYP3A4ALDH1A1HAO1 | |
| SCHEMBL31353019 | 0.78 | TSHR (0.50) | CYP1A2CNR2CYP3A4ALDH1A1PAM | |
| SCHEMBL17866584 | 0.77 | CNR2 (0.45) | CYP1A2CNR2ALDH1A1HAO1PAM | |
| SCHEMBL17866583 | 0.77 | CNR2 (0.45) | CYP1A2CNR2ALDH1A1HAO1PAM | |
| SCHEMBL17866582 | 0.77 | CNR2 (0.45) | CYP1A2CNR2ALDH1A1HAO1PAM | |
| SCHEMBL4250754 | 0.75 | CYP1A2 (0.50) | CYP1A2CNR2CYP3A4ALDH1A1HAO1 | |
| SCHEMBL10707786 | 0.75 | PAM (0.44) | CYP1A2ALDH1A1HAO1PAMTET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648229-B1 | HYALURONIC ACID AND DERIVATIVES THEREOF IN INTERPENETRATING POLYMER NETWORKS (IPN) | MURST ITALIAN (IT) | 1998-05-06 | — | — | EP | disclosed |
| US-5644049-A | Biomaterial comprising hyaluronic acid and derivatives thereof in interpenetrating polymer networks (IPN) | M.U.R.S.T. ITALIAN MINISTRY FOR UNIVERSITITES AND SCIENTIFIC AND TECHNOLOGY RESEARCH (IT) | 1997-07-01 | — | — | US | disclosed |