Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732666 | 0.90 | HPGD (0.50) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8733049 | 0.89 | HPGD (0.46) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8732682 | 0.89 | HPGD (0.51) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8735213 | 0.89 | HPGD (0.54) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8730812 | 0.85 | L3MBTL1 (0.43) | HPGDALDH1A1CYP1A2POLBRAB9A | |
| SCHEMBL8735032 | 0.80 | HPGD (0.46) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8735053 | 0.78 | HPGD (0.47) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8730869 | 0.78 | CDC7 (0.37) | ALDH1A1POLBLMNAL3MBTL1GAA | |
| SCHEMBL8732709 | 0.78 | HPGD (0.49) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8735082 | 0.77 | HPGD (0.49) | HPGDALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749416-B1 | SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO CO (US) | 1998-12-23 | — | — | EP | disclosed |