Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061253 | 0.95 | PDK2 (0.37) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL19061282 | 0.95 | PDK2 (0.37) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL19061799 | 0.94 | KDM4E (0.34) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL19061537 | 0.94 | KDM4E (0.34) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL15887831 | 0.93 | KDM4E (0.34) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL19061212 | 0.93 | PDK2 (0.36) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL17809339 | 0.93 | KDM4E (0.33) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL19061497 | 0.93 | PDK2 (0.36) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL8735734 | 0.93 | KDM4E (0.35) | KDM4EL3MBTL1ATMPDK2HDAC4 | |
| SCHEMBL17245793 | 0.93 | KDM4E (0.35) | KDM4EL3MBTL1ATMPDK2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266851-B2 | Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-02-23 | — | — | US | disclosed |
| US-9266851-B2 | Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-02-23 | — | — | US | disclosed |
| US-20120126217-A1 | FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | IDEMITSU KOSAN CO. LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20120126217-A1 | FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | IDEMITSU KOSAN CO. LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126217-A1 | FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | NR0B2, AFF2, AFF1 | KDM4E 2744/4885L3MBTL1 3195/4885ATM 4148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.