SCHEMBL8735335

SCHEMBL8735335

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)nc(-c4ccc5c(c4)C(C)(C)c4ccccc4-5)n3)cc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ LMNA P02545 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ PDK2 Q15119 6/20 0.33
▸ FLT3 P36888 2/20 0.33
▸ BMX P51813 1/20 0.33
▸ GLA P06280 1/20 0.32
▸ ACACA Q13085 1/20 0.32
▸ TUBB4A P04350 1/20 0.31
▸ TUBB P07437 1/20 0.31
▸ TUBA3C P0DPH7 1/20 0.31
▸ TUBA1B P68363 1/20 0.31
▸ TUBA4A P68366 1/20 0.31
▸ TUBB4B P68371 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736109 1.00 KDM4E (0.34) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL8736940 0.98 MEN1 (0.38) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL8734490 0.98 MEN1 (0.38) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL8735720 0.97 MEN1 (0.36) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL18565872 0.96 PDK2 (0.33) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL8736116 0.96 KDM4E (0.36) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL19271501 0.95 KDM4E (0.36) KDM4EATML3MBTL1PDK2FLT3
SCHEMBL8735745 0.95 KDM4E (0.36) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL8734511 0.95 MEN1 (0.35) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL18385685 0.94 PDK2 (0.32) KDM4EMEN1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NR0B2, AFF2, AFF1 KDM4E 2744/4885MEN1 2878/4885ALDH1A1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback