⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456087 | 0.75 | — | — | |
| SCHEMBL691480 | 0.73 | TP53 (0.33) | — | |
| SCHEMBL9234821 | 0.73 | TRPA1 (0.36) | — | |
| SCHEMBL27358448 | 0.71 | — | — | |
| SCHEMBL21987085 | 0.71 | — | — | |
| SCHEMBL7717133 | 0.67 | HIF1A (0.43) | — | |
| SCHEMBL11196219 | 0.67 | — | — | |
| SCHEMBL27763263 | 0.67 | — | — | |
| SCHEMBL28524814 | 0.67 | — | — | |
| SCHEMBL4361531 | 0.66 | CYP2A6 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| EP-1475370-B1 | OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUI CHEMICALS INC (JP) | 2009-08-05 | — | — | EP | claimed |
| CN-101423518-A | Imidazole derivative and medical application thereof | HUTCHISON MEDIPHARMA SHANGHAI (CN) | 2009-05-06 | — | — | CN | claimed |
| US-7271185-B2 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2007-09-18 | — | — | US | claimed |
| US-20050085521-A1 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2005-04-21 | — | — | US | claimed |
| EP-1475370-A1 | OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-11-10 | — | — | EP | claimed |
| CN-115300640-A | Novel linkers and their use for specific coupling of drugs and biomolecules | 杭州多禧生物科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-113336540-B | Ceramic green sheet and coated sheet | 可乐丽欧洲有限责任公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-111841646-B | Ethylene oligomerization catalyst, preparation method and application thereof | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-108289964-B | Novel linkers and their use for specific coupling of drugs and biomolecules | 杭州多禧生物科技有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110168021-B | Slurry composition, ceramic green sheet and coated sheet | 株式会社可乐丽 | 2022-03-15 | — | — | CN | disclosed |
| CN-113698335-A | Specific conjugation of cell binding molecules | 杭州多禧生物科技有限公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| EP-1475370-B1 | OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUI CHEMICALS INC (JP) | 2009-08-05 | — | — | EP | disclosed |
| CN-101289694-A | Nucleic acid for enhancing synthesis of 2-acetyl-1-pyrrole of plant and fungus | NAT SCIENCE AND TECHNOLOGY DEV (TH) | 2008-10-22 | — | — | CN | disclosed |
| US-7271185-B2 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2007-09-18 | — | — | US | disclosed |
| US-20050085521-A1 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2005-04-21 | — | — | US | disclosed |
| EP-1475370-A1 | OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-11-10 | — | — | EP | disclosed |