SCHEMBL8735558

SCHEMBL8735558

c1ccc(-c2ccc3c(c2)c2cnccc2n3-c2cccc(-c3cccc(-c4c5ccccc5c(-c5ccccc5)c5ccccc45)n3)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.34
▸ MAPK10 P53779 1/20 0.33
▸ PDE10A Q9Y233 1/20 0.33
▸ CYP19A1 P11511 1/20 0.33
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ALOX5 P09917 1/20 0.32
▸ HSP90AA1 P07900 1/20 0.32
▸ TNF P01375 1/20 0.32
▸ GRM5 P41594 3/20 0.32
▸ NPY5R Q15761 1/20 0.31
▸ DHODH Q02127 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ KARS1 Q15046 1/20 0.31
▸ MAOA P21397 2/20 0.30
▸ MAOB P27338 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12169047 0.94 KMT2A (0.33) MAPTMAPK10CYP19A1MEN1KMT2A
SCHEMBL6113769 0.91 MAPT (0.36) MAPTMAPK10PDE10AMEN1KMT2A
SCHEMBL12169093 0.91 KMT2A (0.33) MAPTMAPK10CYP19A1MEN1KMT2A
SCHEMBL15432052 0.90 ATM (0.34) MAPTMAPK10CYP19A1MEN1KMT2A
SCHEMBL9921893 0.90 MAOA (0.37) MAPTCYP19A1MEN1KMT2AALOX5
SCHEMBL21700031 0.90 PSD (0.37) MAPTMEN1KMT2ARAB9A
SCHEMBL12442765 0.89 MAOA (0.36) MAPTMAPK10CYP19A1MEN1KMT2A
SCHEMBL15432053 0.89 KMT2A (0.33) MAPTMAPK10CYP19A1MEN1KMT2A
SCHEMBL21249193 0.89 KDM4E (0.36) MAPTMAPK10PDE10AMEN1KMT2A
SCHEMBL17618094 0.88 MAPT (0.32) MAPTMAPK10CYP19A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9755152-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-05 — — US disclosed
US-9755152-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-05 — — US disclosed
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2015-06-04 — — US disclosed
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2015-06-04 — — US disclosed
US-8927119-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-01-06 — — US disclosed
US-8927119-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-01-06 — — US disclosed
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-05-24 — — US disclosed
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, PNPO, SLCO2A1 MAPT 1945/4885MAPK10 1767/4885PDE10A 3914/4885
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, PNPO, SLCO2A1 MAPT 1945/4885MAPK10 1767/4885PDE10A 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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