Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763880 | 0.86 | MEN1 (0.34) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8729780 | 0.85 | GABRA1 (0.38) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8730124 | 0.85 | SLC22A12 (0.34) | — | |
| SCHEMBL8854428 | 0.84 | SCN8A (0.33) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8735584 | 0.84 | ATM (0.36) | MEN1KMT2ATSHRMAPTKDM4E | |
| SCHEMBL8729877 | 0.83 | STK10 (0.33) | P2RX7 | |
| SCHEMBL8732732 | 0.82 | KCNK3 (0.41) | KMT2AKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL8412043 | 0.81 | MEN1 (0.38) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8730132 | 0.81 | AR (0.33) | — | |
| SCHEMBL8854419 | 0.81 | SCN8A (0.36) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699390-B1 | Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use | ROHM & HAAS (US) | 1998-10-07 | — | — | EP | claimed |