Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.67 |
| ▸ | CES1 | P23141 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305314 | 0.97 | CES2 (0.63) | CES2CES1HDAC8HDAC6TSHR | |
| Water SCHEMBL27559365 | 0.97 | CES2 (0.63) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6159646 | 0.97 | CES2 (0.72) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL18199938 | 0.97 | CES2 (0.72) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL2650157 | 0.97 | CES2 (0.72) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL25248339 | 0.97 | CES2 (0.63) | CES2CES1HDAC8HDAC6TSHR | |
| Water SCHEMBL27570807 | 0.94 | CES2 (0.68) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL873874 | 0.94 | — | — | |
| Methyl Alcohol SCHEMBL909941 | 0.92 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| Benzene SCHEMBL27623531 | 0.92 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129398-A1 | POLYPEPTIDE AND METHOD FOR PRODUCING AMINO ACID USING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-04-24 | — | — | US | claimed |
| CN-118401654-A | Polypeptide and method for preparing amino acid using same | 中外制药株式会社 | 2024-07-26 | — | — | CN | claimed |
| WO-2023127752-A1 | POLYPEPTIDE AND METHOD FOR PRODUCING AMINO ACID USING SAME | 中外製薬株式会社 | 2023-07-06 | — | — | WO | claimed |
| EP-4206322-A2 | POLYPEPTIDE AND METHOD FOR PRODUCING AMINO ACID USING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-07-05 | — | — | EP | claimed |
| EP-2822682-B1 | MICROCAPSULES AND USES THEREOF | FIRMENICH & CIE (CH) | 2017-04-26 | — | — | EP | claimed |
| CN-104994732-A | Composition comprising peroxyacid | CHD BIOSCIENCE INC | 2015-10-21 | — | — | CN | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| US-7550277-B2 | D-amino acid dehydrogenase and method of making D-amino acids | CODEXIS, INC. (US) | 2009-06-23 | — | — | US | claimed |
| US-20080182972-A1 | D-amino acid dehydrogenase and method of making D-amino acids | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2008-07-31 | — | — | US | claimed |
| EP-1896574-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BioCatalytics Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2006113085-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BIOCATALYTICS, INC. (US) | 2006-10-26 | — | — | WO | claimed |
| US-20250369029-A1 | METHOD FOR PRODUCING AMINO ACID AND PEPTIDE COMPOUND, USING ENZYME AND ADDITIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2025-12-04 | — | — | US | disclosed |
| US-20250129398-A1 | POLYPEPTIDE AND METHOD FOR PRODUCING AMINO ACID USING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-04-24 | — | — | US | disclosed |
| EP-4520829-A1 | METHOD FOR PRODUCING AMINO ACID AND PEPTIDE COMPOUND, USING ENZYME AND ADDITIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-03-12 | — | — | EP | disclosed |
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-4369206-A | HARDENING COATING WITH AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | disclosed |
| EP-0008626-A1 | Ammonium salts of alpha-ketocarboxylic acids, their use in the preparation of amines and coating materials containing them | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | PDE4A, PDE4B, PDE4D | CES2 584/4885CES1 743/4885HDAC8 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.