SCHEMBL8735712

SCHEMBL8735712

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4ccccc4)cc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)n3)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.38
▸ L3MBTL1 Q9Y468 3/20 0.38
▸ ATM Q13315 1/20 0.38
▸ MEN1 O00255 9/20 0.36
▸ KMT2A Q03164 9/20 0.36
▸ HPGD P15428 9/20 0.36
▸ MAPT P10636 8/20 0.36
▸ ALDH1A1 P00352 8/20 0.36
▸ NTSR1 P30989 1/20 0.36
▸ LMNA P02545 3/20 0.35
▸ TDP1 Q9NUW8 3/20 0.34
▸ MAPK1 P28482 2/20 0.34
▸ HDAC4 P56524 1/20 0.34
▸ CYP2C19 P33261 2/20 0.33
▸ ACACA Q13085 2/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ GLA P06280 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8737001 0.98 KDM4E (0.36) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8735460 0.97 KMT2A (0.38) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8735792 0.97 KMT2A (0.38) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8735674 0.97 KDM4E (0.36) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8736945 0.96 MEN1 (0.37) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8735330 0.96 MEN1 (0.37) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL17899175 0.96 KMT2A (0.37) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8735731 0.96 MEN1 (0.37) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL8734507 0.96 MEN1 (0.37) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL17899169 0.96 KMT2A (0.37) KDM4EL3MBTL1ATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NR0B2, AFF2, AFF1 KDM4E 2744/4885L3MBTL1 3195/4885ATM 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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