Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686859 | 0.85 | APP (0.41) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3791702 | 0.80 | APP (0.57) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6742524 | 0.77 | MAPT (0.53) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5872241 | 0.77 | MAPT (0.42) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2746036 | 0.74 | APP (0.38) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7191517 | 0.72 | HAO1 (0.44) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3786925 | 0.72 | APP (0.57) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3792911 | 0.71 | APP (0.63) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3796509 | 0.71 | APP (0.80) | APPNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5872247 | 0.70 | MAPT (0.50) | APPNPC1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854849-A1 | ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997010193-A1 | ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF | THE DOW CHEMICAL COMPANY (US) | 1997-03-20 | — | — | WO | disclosed |