Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742524 | 0.89 | MAPT (0.53) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL3839249 | 0.86 | MAPT (0.59) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL5872241 | 0.84 | MAPT (0.42) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL2746893 | 0.82 | NPC1 (0.43) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL5372913 | 0.79 | GAA (0.50) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7061161 | 0.78 | ALDH1A1 (0.66) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28911864 | 0.77 | CYP1A2 (0.47) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28235528 | 0.77 | PYGL (0.51) | NPC1KDM4ERAB9APOLBHAO1 | |
| SCHEMBL2114742 | 0.77 | APP (0.75) | MAPTNPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL5871989 | 0.77 | APP (0.75) | MAPTNPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049386-B2 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. (US) | 2006-05-23 | — | — | US | disclosed |
| EP-1309639-A4 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INT INC (US) | 2004-12-08 | — | — | EP | disclosed |
| US-6803441-B2 | INCORPORATING THERMOSETTING MONOMER HAS A CAGE COMPOUND OR ARYL CORE STRUCTURE, PLURALITY OF ARMS THAT ARE COVALENTLY BOUND TO THE CAGE COMPOUND OR CORE STRUCTURE INTO A POLYMER TO FORM THE LOW DIELECTRIC CONSTANT POLYMER | HONEYWELL INTERNATIONAL INC. | 2004-10-12 | — | — | US | disclosed |
| US-20040192870-A1 | Compositions and methods for thermosetting molecules in organic compositions | LAU KREISLER S (US) | 2004-09-30 | — | — | US | disclosed |
| WO-2004000909-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030096938-A1 | Compositions and methods for thermosetting molecules in organic compositions | LAU KREISLER (US) | 2003-05-22 | — | — | US | disclosed |
| EP-1309639-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | Honeywell International, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20030060590-A1 | Producing a low dielectric constant polymer from a thermosetting monomer that has a cage compound or aryl core structure, which is covalently bound to a plurality of arms that contain acetylenic groups | HONEYWELL INTERNATIONAL INC. | 2003-03-27 | — | — | US | disclosed |
| US-6469123-B1 | THERMOSETTING MONOMER IS INCORPORATED INTO A POLYMER TO FORM THE LOW DIELECTRIC CONSTANT POLYMER; CAGE COMPOUNDS AND CORE STRUCTURES INCLUDE ADAMANTANE, DIAMANTANE, SILICON, A PHENYL GROUP AND A SEXIPHENYLENE | HONEYWELL INTERNATIONAL INC. | 2002-10-22 | — | — | US | disclosed |
| US-20020022708-A1 | Compositions and methods for thermosetting molecules in organic compositions | HONEYWELL INTERNATIONAL INC. | 2002-02-21 | — | — | US | disclosed |
| WO-2002008308-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2002-01-31 | — | — | WO | disclosed |