Methane

Methane

SCHEMBL8735853

C.CC(C)CCC(C(=O)O)(C(=O)O)C(=O)O.CC(C)CCC(C(=O)O)(C(=O)O)C(=O)O.CC(C)CCC(C(=O)O)(C(=O)O)C(=O)O

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.37
BLM P54132 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRA3 P34903 2/20 0.31
GABRA2 P47869 2/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5551502 0.81 ACACB (0.44) CA1BLMACACBACACA
SCHEMBL21328423 0.79 ACACB (0.42) CA1BLMACACBACACA
SCHEMBL28470872 0.78 GABRR1 (0.50) BLMACACBACACACYP1A2
SCHEMBL7783900 0.77 CA1 (0.39) CA1BLML3MBTL1SLC1A3SLC1A2
SCHEMBL2033747 0.75 TET2 (0.41) CA1BLML3MBTL1SLC1A3SLC1A2
SCHEMBL2748871 0.75 L3MBTL1 (0.38) CA1BLML3MBTL1SLC1A3SLC1A2
SCHEMBL2718566 0.75 ACACB (0.52) CA1BLML3MBTL1SLC1A3SLC1A2
SCHEMBL12868851 0.73 CA1 (0.36) CA1BLML3MBTL1SLC1A3SLC1A2
SCHEMBL29836715 0.73 CA1 (0.36) CA1BLML3MBTL1SLC1A3SLC1A2
SCHEMBL17376935 0.71 CA1 (0.34) CA1BLML3MBTL1SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718272-B1 Process for the preparation of derivatives of trialkyle esters LONZA AG (CH) 1998-11-18 EP disclosed
EP-0718272-A1 Process for the preparation of derivatives of trialkyle esters LONZA AG (CH) 1996-06-26 EP disclosed