Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903022 | 0.83 | ERN1 (0.43) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL8736485 | 0.83 | ERN1 (0.39) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL1811781 | 0.81 | ERN1 (0.38) | ERN1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL20088346 | 0.81 | ERN1 (0.57) | ERN1TDP1ALDH1A1 | |
| SCHEMBL30402820 | 0.81 | ERN1 (0.52) | ERN1TDP1 | |
| SCHEMBL10540806 | 0.79 | ERN1 (0.36) | ERN1TDP1 | |
| SCHEMBL6495322 | 0.78 | TDP1 (0.46) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL1312079 | 0.77 | CYP3A4 (0.50) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL1809938 | 0.75 | ERN1 (0.36) | ERN1TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL7557637 | 0.74 | MEN1 (0.38) | ERN1TDP1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653412-B1 | Process for preparing 4,5-difluorobenzaldehydes | BAYER AG (DE) | 1998-01-21 | — | — | EP | disclosed |
| US-5489715-A | Process for preparing 4,5-difluorobenzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0653412-A1 | Process for preparing 4,5-difluorobenzaldehydes | BAYER AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| EP-0583705-A1 | Process for the preparation of 2,3,4-trichloro-5-fluoro-benzoylchloride | BAYER AG (DE) | 1994-02-23 | — | — | EP | disclosed |