Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695302 | 0.79 | TDP1 (0.38) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL9790158 | 0.75 | ALDH1A1 (0.44) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL8735857 | 0.74 | ERN1 (0.44) | MEN1KMT2AALDH1A1CYP3A4ERN1 | |
| SCHEMBL7042635 | 0.74 | KHK (0.44) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL7557630 | 0.73 | ALDH1A1 (0.38) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL5704384 | 0.72 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL14408183 | 0.72 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL7557377 | 0.72 | TRPV4 (0.39) | TRPV4ERN1 | |
| SCHEMBL25992030 | 0.72 | TRPV4 (0.43) | TRPV4ERN1 | |
| SCHEMBL5704367 | 0.72 | KMT2A (0.41) | MEN1MAPTKMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977729-B1 | 3-CYANO-2,4,5-TRIFLUORO-BENZOYL FLUORIDE AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BAYER AG (DE) | 2002-03-13 | — | — | EP | claimed |