Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508991 | 0.83 | PARP1 (0.51) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL11023694 | 0.83 | ALDH1A1 (0.51) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10511436 | 0.81 | ALDH1A1 (0.46) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10508663 | 0.80 | PARP1 (0.56) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10509845 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10507388 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10756857 | 0.78 | PARP1 (0.46) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL29505933 | 0.78 | ALDH1A1 (0.46) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10508752 | 0.78 | TDP1 (0.43) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 | |
| SCHEMBL10758186 | 0.78 | DAO (0.47) | ALDH1A1PARP1PRKCIPDE4BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129845-A1 | Inhibitors of Bruton's Tyrosine Kinase | DEWDNEY NOLAN JAMES (HK) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129845-A1 | Inhibitors of Bruton's Tyrosine Kinase | BTK, SYK, LYN | ALDH1A1 4560/4885PARP1 1973/4885PRKCI 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.