SCHEMBL8735949

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9921665	0.81	CYP11B1 (0.38)	CYP11B1CYP11B2DHODHMAPK9MAPK10
	SCHEMBL12442764	0.80	PIK3CA (0.41)	PIK3CDPIK3CAMTORCYP1A2METAP2
	SCHEMBL18272719	0.79	CYP17A1 (0.43)	PIK3CDPIK3CAMTORCYP11B1CYP11B2
	SCHEMBL12169038	0.78	CYP11B1 (0.39)	PIK3CDPIK3CAMTORCYP11B1CYP11B2
	SCHEMBL12169065	0.78	CYP11B1 (0.38)	PIK3CDPIK3CAMTORCYP11B1CYP11B2
	SCHEMBL13658703	0.77	MAPK9 (0.48)	CYP1A2CYP11B1CYP11B2DHODHMAPK9
	SCHEMBL6114261	0.77	CYP11B1 (0.41)	CYP11B1CYP11B2MAPK9MAPK10CYP17A1
	SCHEMBL9890903	0.77	TUBB4A (0.41)	PIK3CDPIK3CAMTORCYP1A2CYP11B1
	SCHEMBL12919317	0.76	KDM4E (0.39)	AOC3MEN1KMT2AMAPK10CDK4
	SCHEMBL8736819	0.76	CYP11B1 (0.43)	PIK3CDPIK3CAMTORCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.