SCHEMBL8735978

SCHEMBL8735978

CCC(C(=O)O)(C(=O)O)C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
RECQL P46063 2/20 0.35
EPHX1 P07099 3/20 0.34
CHRM2 P08172 4/20 0.34
CHRM1 P11229 4/20 0.34
KCNH2 Q12809 3/20 0.34
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 2/20 0.34
CHRM4 P08173 2/20 0.34
CHRM3 P20309 2/20 0.34
SLC6A3 Q01959 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
ABCB11 O95342 1/20 0.34
ESR1 P03372 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21269191 0.98 KEAP1 (0.36) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL21269331 0.98 KEAP1 (0.36) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL28315744 0.98 KEAP1 (0.36) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL28875942 0.98 KEAP1 (0.36) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL28315750 0.98 KEAP1 (0.36) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL21269269 0.98 KEAP1 (0.36) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL8734148 0.98 KEAP1 (0.38) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL28314525 0.96 KEAP1 (0.35) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL28314603 0.96 KEAP1 (0.35) KEAP1NFE2L2RECQLEPHX1CHRM2
SCHEMBL28314379 0.96 KEAP1 (0.35) KEAP1NFE2L2RECQLEPHX1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640886-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2018-04-27 CN disclosed
CN-104640887-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2017-08-29 CN disclosed
CN-105837714-A METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER 东邦钛株式会社 2016-08-10 CN disclosed
CN-104640886-A PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104640887-A Production method for solid catalyst component for polymerizing olefins, catalyst for polymerizing olefins, and production method for polymerized olefins TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104470953-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2015-03-25 CN disclosed
US-5716973-A ADMINISTERING DIFLUORO STATONE ANALOGS MERRELL PHARMACEUTICALS INC. (US) 1998-02-10 US disclosed
US-5559140-A VIRICIDES MERRELL PHARMACEUTICALS INC. (US) 1996-09-24 US disclosed
EP-0565631-B1 ANTI-VIRAL COMPOUNDS MERRELL PHARMA INC (US) 1996-09-18 EP disclosed
EP-0565631-A1 ANTI-VIRAL COMPOUNDS. MERRELL DOW PHARMA (US) 1993-10-20 EP disclosed
WO-1992012123-A1 ANTI-VIRAL COMPOUNDS MERRELL DOW PHARMACEUTICALS INC. (US) 1992-07-23 WO disclosed