Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175786 | 0.90 | CYP3A4 (0.35) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8855614 | 0.88 | MAPT (0.52) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL11644077 | 0.87 | MAPT (0.51) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8855484 | 0.87 | MAPT (0.51) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL11179297 | 0.85 | MAPT (0.33) | MAPTALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL11183105 | 0.85 | MAPT (0.33) | MAPTALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL11187021 | 0.85 | HTT (0.36) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8855536 | 0.84 | CYP3A4 (0.49) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8855544 | 0.84 | MAPT (0.46) | MAPTALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8855556 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5635490-A | ADMINISTERING POLYETHER ANTIBIOTIC AND BENZIMIDAZOLE DERIVATIVE | ELI LILLY AND COMPANY (US) | 1997-06-03 | — | — | US | claimed |
| EP-0113945-A1 | Amine salts | ELI LILLY AND COMPANY (US) | 1984-07-25 | — | — | EP | claimed |
| US-4421759-A | Methods for controlling fire ants | ELI LILLY AND COMPANY (US) | 1983-12-20 | — | — | US | claimed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | claimed |
| EP-4225921-A1 | METHODS FOR X CHROMOSOME REACTIVATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076529-A1 | METHODS FOR X CHROMOSOME REACTIVATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-14 | — | — | WO | disclosed |
| EP-0821953-A2 | Anticoccidial methods and feedstuffs | ELI LILLY AND COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0616806-A1 | Phenylenediamine or benzimidazole derivatives for treating coccidiosis | ELI LILLY AND COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0113945-A1 | Amine salts | ELI LILLY AND COMPANY (US) | 1984-07-25 | — | — | EP | disclosed |
| US-4421759-A | Methods for controlling fire ants | ELI LILLY AND COMPANY (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0031699-A1 | Benzimidazoline salts, their preparation and compositions containing them | ELI LILLY AND COMPANY (US) | 1981-07-08 | — | — | EP | disclosed |
| US-4265901-A | HERBICIDES, INSECTICIDES, PARASITICIDES | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |