SCHEMBL8736227

SCHEMBL8736227

CC1COC1COCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843935 0.85
SCHEMBL3845559 0.85
SCHEMBL3845121 0.85
SCHEMBL6532014 0.80 TSHR (0.38) TSHRMAPK1
SCHEMBL24388694 0.78 TSHR (0.50) TSHRMAPK1
SCHEMBL3906677 0.78 TSHR (0.50) TSHRMAPK1
SCHEMBL3909386 0.78 TSHR (0.50) TSHRMAPK1
SCHEMBL3906609 0.78 TSHR (0.50) TSHRMAPK1
SCHEMBL3906672 0.78 TSHR (0.50) TSHRMAPK1
SCHEMBL3901860 0.78 TSHR (0.50) TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811004-A4 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET GENERAL CO (US) 1998-09-30 EP disclosed
EP-0811004-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1997-12-10 EP disclosed