SCHEMBL6532014

SCHEMBL6532014

CC1COC1COCC(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736227 0.80 TSHR (0.33) TSHRMAPK1
SCHEMBL13172665 0.75
SCHEMBL18290484 0.73 TSHR (0.61) TSHRMAPK1ALDH1A1
SCHEMBL2547812 0.73 TSHR (0.61) TSHRMAPK1ALDH1A1
SCHEMBL16854634 0.73 TSHR (0.61) TSHRMAPK1ALDH1A1
SCHEMBL8736904 0.72 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3845121 0.71
SCHEMBL3845559 0.71
SCHEMBL3843935 0.71
SCHEMBL16300481 0.69 SMN1; SMN2 (0.60) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6962966-B2 Monohydric polyfluorooxetane oligomers, polymers, and copolymers and coatings containing the same OMNOVA SOLUTIONS INC. (US) 2005-11-08 US disclosed
US-6927276-B2 Monohydric polyfluorooxetane oligomers, polymers, and copolymers and coating containing the same OMNOVA SOLUTIONS INC. (US) 2005-08-09 US disclosed
EP-1161479-A1 POLYESTER WITH PARTIALLY FLUORINATED SIDE CHAINS OMNOVA SOLUTIONS INC. (US) 2001-12-12 EP disclosed
WO-2000046270-A1 POLYESTER WITH PARTIALLY FLUORINATED SIDE CHAINS OMNOVA SOLUTIONS INC. (US) 2000-08-10 WO disclosed