Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328560 | 1.00 | HPGD (0.44) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL6328564 | 1.00 | HPGD (0.44) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL3370115 | 0.79 | HPGD (0.49) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL3370114 | 0.79 | HPGD (0.49) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL30363500 | 0.79 | HPGD (0.49) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL10041963 | 0.79 | HPGD (0.49) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL8886079 | 0.76 | CYP19A1 (0.45) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL6181741 | 0.75 | HPGD (0.41) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 | |
| SCHEMBL7170156 | 0.72 | CYP19A1 (0.52) | HPGDL3MBTL1CYP19A1 | |
| SCHEMBL12460878 | 0.72 | HPGD (0.39) | HPGDL3MBTL1MAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783573-A | Pharmaceuticals which promote gastrointestinal blood circulation | SOLVAY PHARMACEUTICALS GMBH (DE) | 1998-07-21 | — | — | US | disclosed |
| US-4600534-A | Process and intermediates for manufacture of 3-(5-amino-1-carboxypentylamino)-tetrahydro-1-benzazepin-2-one-1-acetic acid | CIBA-GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |