Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263075 | 0.83 | HRH1 (0.39) | HPGDL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL5263072 | 0.83 | HRH1 (0.39) | HPGDL3MBTL1ALDH1A1TSHRLMNA | |
| SCHEMBL11244575 | 0.83 | HPGD (0.38) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL10041963 | 0.78 | HPGD (0.49) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL3370114 | 0.78 | HPGD (0.49) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL3370115 | 0.78 | HPGD (0.49) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL30363500 | 0.78 | HPGD (0.49) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL6328560 | 0.75 | HPGD (0.44) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL6328564 | 0.75 | HPGD (0.44) | HPGDL3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL8736255 | 0.75 | HPGD (0.44) | HPGDL3MBTL1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392317-A4 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | ANTEXPHARMA INC (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1392317-A2 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | Antexpharma, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100327-A2 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | ANTEXPHARMA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-0179667-B1 | N6-SUBSTITUTED ADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |