Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452903 | 1.00 | PDE2A (0.32) | PDE2AHTR2AHTR2CHTR2BNOTUM | |
| SCHEMBL8451372 | 0.85 | KDM1A (0.33) | PDE2ANOTUM | |
| SCHEMBL13002301 | 0.85 | KDM1A (0.33) | PDE2ANOTUM | |
| SCHEMBL8736458 | 0.82 | CES2 (0.30) | — | |
| SCHEMBL7859003 | 0.82 | CES2 (0.30) | — | |
| SCHEMBL13002679 | 0.81 | KDM1A (0.30) | — | |
| SCHEMBL8446783 | 0.81 | KDM1A (0.30) | — | |
| SCHEMBL13002307 | 0.81 | PDE2A (0.31) | PDE2A | |
| SCHEMBL9260081 | 0.81 | PDE2A (0.31) | PDE2A | |
| SCHEMBL8835644 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688754-B1 | DICYCLOHEXYLETHYLENE DERIVATIVE | CHISSO CORP (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5641432-A | USEFUL IN LIQUID CRYSTAL COMPOSITIONS; WIDE LIQUID CRYSTAL PHASE TEMPERATURE RANGE, LOW VISCOSITY, HIGH STABILITY; COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS | CHISSO CORPORATION (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0688754-A1 | DICYCLOHEXYLETHYLENE DERIVATIVE | CHISSO CORPORATION (JP) | 1995-12-27 | — | — | EP | disclosed |