Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941504 | 0.93 | FOLH1 (0.50) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL7942090 | 0.91 | FOLH1 (0.52) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL7932889 | 0.89 | FOLH1 (0.50) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL8856829 | 0.83 | FOLH1 (0.44) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7941425 | 0.83 | FOLH1 (0.56) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL30018936 | 0.72 | FOLH1 (0.62) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL108166 | 0.71 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL4810549 | 0.71 | LMNA (0.47) | NAALAD2 | |
| SCHEMBL31526897 | 0.70 | FOLH1 (0.82) | FOLH1GRM3NAALAD2CPA3 | |
| SCHEMBL13726298 | 0.69 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735998-B1 | PROCESS FOR PREPARING MICHAEL ADDITION PRODUCTS | ALBEMARLE CORP (US) | 1998-10-14 | — | — | EP | disclosed |
| EP-0735998-A1 | PROCESS FOR PREPARING MICHAEL ADDITION PRODUCTS | ALBEMARLE CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017368-A1 | PROCESS FOR PREPARING MICHAEL ADDITION PRODUCTS | ALBEMARLE CORPORATION (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5347043-A | REACTING A DIALKYL MALONATE WITH AT LEAST THREE MOLAR PROPORTIONS OF AN ALKYL ACRYLATE IN THE PRESENCE OF A BASIC INITIATOR AND A PHASE TRANSFER CATALYST | ALBEMARLE CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |