Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331537 | 0.81 | ALDH1A1 (0.39) | ALDH1A1POLBGAAKMT2AMAPT | |
| SCHEMBL6046983 | 0.69 | PIM1 (0.33) | ALDH1A1 | |
| Naphthalene SCHEMBL4378459 | 0.66 | ALDH1A1 (0.65) | ALDH1A1HSP90AA1SLC6A3TSHRKMT2A | |
| SCHEMBL27758324 | 0.65 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTELANE | |
| Fluorene SCHEMBL608981 | 0.65 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMAPTMAPK1 | |
| O-Xylene SCHEMBL27600002 | 0.65 | ALDH1A1 (0.62) | ALDH1A1GAATSHRKDM4EMAPT | |
| Catechol SCHEMBL28249167 | 0.65 | ALDH1A1 (0.62) | ALDH1A1POLBGAATSHRKMT2A | |
| Biphenyl SCHEMBL1395450 | 0.65 | ALDH1A1 (0.62) | ALDH1A1SLC6A3TSHRKDM4EMAPT | |
| Benzene SCHEMBL28395547 | 0.63 | ALDH1A1 (0.83) | ALDH1A1POLBTSHRKMT2AKDM4E | |
| Benzene SCHEMBL27313869 | 0.63 | ALDH1A1 (0.83) | ALDH1A1POLBTSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639619-B1 | A melt-processible blend | ROHM & HAAS (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5405670-A | Transparent blend with methyl methacrylate-tribromophenyl maleimide | ROHM AND HAAS COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0639619-A2 | A melt-processible blend | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |