Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941640 | 0.88 | MAPT (0.47) | ERN1NPC1RAB9AMAPTGRM5 | |
| SCHEMBL29496951 | 0.79 | NPC1 (0.67) | NPC1RAB9AMAPTGRM5PDE4D | |
| SCHEMBL29496950 | 0.79 | NPC1 (0.67) | NPC1RAB9AMAPTGRM5PDE4D | |
| SCHEMBL2643483 | 0.79 | NPC1 (0.67) | NPC1RAB9AMAPTGRM5PDE4D | |
| SCHEMBL5734991 | 0.77 | ERN1 (0.54) | ERN1MAPTALDH1A1PELI1KDM4E | |
| SCHEMBL7359628 | 0.76 | PDE4A (0.47) | ERN1MAPTPDE4AALDH1A1PELI1 | |
| SCHEMBL7350348 | 0.76 | PDE4B (0.61) | NPC1RAB9AMAPTPDE4DPDE4A | |
| SCHEMBL18605359 | 0.75 | MAPT (0.52) | ERN1NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7231457 | 0.73 | PDE4D (0.61) | NPC1RAB9AMAPTPDE4DPDE4A | |
| SCHEMBL7137309 | 0.73 | ERN1 (0.52) | ERN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10114724-A | — | — | None | — | — | JP | disclosed |
| JP-H10114724-A | NEW SUBSTITUTED BIPHENYL OR PHENYLPYRIDINE COMPOUND, ITS PRODUCTION AND MEDICINAL COMPOSITION CONTAINING THE SAME | ADIR | 1998-05-06 | — | — | JP | disclosed |