Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736393 | 0.88 | ERN1 (0.52) | MAPTNPC1RAB9AGRM5ALDH1A1 | |
| SCHEMBL7348579 | 0.82 | PDE4A (0.45) | MAPTNPC1RAB9AGRM5ALDH1A1 | |
| SCHEMBL7348572 | 0.82 | PDE4A (0.45) | MAPTNPC1RAB9AGRM5ALDH1A1 | |
| SCHEMBL7941636 | 0.77 | ALDH1A1 (0.44) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL7349224 | 0.77 | F7 (0.46) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL7349221 | 0.77 | F7 (0.46) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL7356489 | 0.77 | POLB (0.44) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL7356481 | 0.77 | POLB (0.44) | MAPTNPC1RAB9AALDH1A1POLB | |
| SCHEMBL29496950 | 0.76 | NPC1 (0.67) | MAPTNPC1RAB9AGRM5ALDH1A1 | |
| SCHEMBL29496951 | 0.76 | NPC1 (0.67) | MAPTNPC1RAB9AGRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | claimed |
| CN-1189493-A | New Substituted biphenyl or phenylpyridine compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-08-05 | — | — | CN | claimed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | claimed |