SCHEMBL8736394

SCHEMBL8736394

[c]1cccc(C2CC[CH]CC2)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
KMO O15229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21118 0.87
SCHEMBL593071 0.83 CYP11B2 (0.39) SLC18A3SIGMAR1KMO
SCHEMBL23110 0.83 CYP11B2 (0.44) SLC18A3SIGMAR1KMO
SCHEMBL23071376 0.81 CYP11B2 (0.47) SLC18A3SIGMAR1KMO
SCHEMBL21454 0.81 CYP11B2 (0.47) SLC18A3SIGMAR1KMO
SCHEMBL677487 0.81 CYP11B2 (0.47) SLC18A3SIGMAR1KMO
SCHEMBL2092662 0.78 SLC18A3 (0.61) SLC18A3SIGMAR1
SCHEMBL27651893 0.78 ESR2 (0.48) SLC18A3SIGMAR1
SCHEMBL652226 0.76 POLB (0.38) SLC18A3SIGMAR1
SCHEMBL60704 0.75 SLC18A3 (0.56) SLC18A3SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850992-A1 Transparent blends of polyetherimide resins GENERAL ELECTRIC COMPANY (US) 1998-07-01 EP disclosed