Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.59 |
| ▸ | NOS3 | P29474 | 4/20 | 0.59 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4611832 | 0.79 | NOS2 (0.79) | NOS2NOS3NOS1LIMK1PRKCI | |
| Trifluoromethanesulfonic Acid SCHEMBL27875541 | 0.78 | NOS2 (0.63) | NOS2NOS3TLR7NOS1LIMK1 | |
| SCHEMBL29814771 | 0.77 | — | — | |
| SCHEMBL34938 | 0.77 | — | — | |
| SCHEMBL28287103 | 0.77 | NOS2 (0.58) | NOS2NOS3NOS1LIMK1PRKCI | |
| Zinc Ion SCHEMBL30519352 | 0.75 | NOS2 (0.95) | NOS2NOS3NOS1LIMK1KDM4E | |
| SCHEMBL30454704 | 0.75 | NOS2 (0.95) | NOS2NOS3NOS1LIMK1KDM4E | |
| SCHEMBL30482664 | 0.75 | NOS2 (0.95) | NOS2NOS3NOS1LIMK1KDM4E | |
| Hydrochloric Acid SCHEMBL11719745 | 0.75 | NOS2 (0.95) | NOS2NOS3NOS1LIMK1KDM4E | |
| SCHEMBL28572816 | 0.75 | NOS2 (0.95) | NOS2NOS3NOS1LIMK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552219-B2 | Process for preparing L-phenyl-3-dimethylaminopropane derivative | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-10-08 | — | — | US | claimed |
| EP-2619174-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | Ind-Swift Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| US-20130190522-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-07-25 | — | — | US | claimed |
| WO-2012038974-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| US-8552219-B2 | Process for preparing L-phenyl-3-dimethylaminopropane derivative | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-10-08 | — | — | US | disclosed |
| US-20130190522-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190522-A1 | PROCESS FOR PREPARING L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVE | CYP3A43, UGT1A1, UGT1A7 | NOS2 1569/4885NOS3 1619/4885TLR7 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.