Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.52 |
| ▸ | CETP | P11597 | 4/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385051 | 0.89 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL31069863 | 0.89 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL25335565 | 0.89 | LPAR1 (0.67) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL10929587 | 0.86 | LPAR1 (0.64) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL8903456 | 0.86 | LPAR1 (0.51) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL30931378 | 0.85 | LPAR1 (0.53) | LPAR1LPAR3CETPLPAR2LPAR5 | |
| SCHEMBL11289762 | 0.84 | LPAR1 (0.50) | LPAR1LPAR3CETPLPAR2TLR2 | |
| SCHEMBL30866263 | 0.84 | LPAR1 (0.53) | LPAR1LPAR3CETPLPAR2TLR2 | |
| SCHEMBL11292726 | 0.84 | LPAR1 (0.50) | LPAR1LPAR3CETPLPAR2TLR2 | |
| SCHEMBL10605748 | 0.83 | PLA2G10 (0.47) | LPAR1LPAR3CETPLPAR2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792275-A4 | IMPROVED ANTIVIRAL PRODRUGS | UNIV CALIFORNIA (US) | 1998-02-25 | — | — | EP | claimed |
| US-5696277-A | CYTOMEGALOVIRUS, HERPES VIRUS | Hostetler, Karl Y. (US) | 1997-12-09 | — | — | US | claimed |
| EP-0792275-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996015132-A1 | IMPROVED ANTIVIRAL PRODRUGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-05-23 | — | — | WO | claimed |